期刊簡介預(yù)計審稿時間： 較慢,6-12周

The journal is particularly interested in studies on the design and synthesis of new genetic circuits and gene products; computational methods in the design of systems; and integrative applied approaches to understanding disease and metabolism.

Topics may include, but are not limited to:

Design and optimization of genetic systems

Genetic circuit design and their principles for their organization into programs

Computational methods to aid the design of genetic systems

Experimental methods to quantify genetic parts, circuits, and metabolic fluxes

Genetic parts libraries: their creation, analysis, and ontological representation

Protein engineering including computational design

Metabolic engineering and cellular manufacturing, including biomass conversion

Natural product access, engineering, and production

Creative and innovative applications of cellular programming

Medical applications, tissue engineering, and the programming of therapeutic cells

Minimal cell design and construction

Genomics and genome replacement strategies

Viral engineering

Automated and robotic assembly platforms for synthetic biology

DNA synthesis methodologies

Metagenomics and synthetic metagenomic analysis

Bioinformatics applied to gene discovery, chemoinformatics, and pathway construction

Gene optimization

Methods for genome-scale measurements of transcription and metabolomics

Systems biology and methods to integrate multiple data sources

in vitro and cell-free synthetic biology and molecular programming

Nucleic acid engineering.

該期刊特別關(guān)注新基因電路和基因產(chǎn)品的設(shè)計和合成研究；系統(tǒng)設(shè)計中的計算方法；以及理解疾病和新陳代謝的綜合應(yīng)用方法。

主題可能包括但不限于：

遺傳系統(tǒng)的設(shè)計和優(yōu)化

遺傳電路設(shè)計及其組織成程序的原理

輔助遺傳系統(tǒng)設(shè)計的計算方法

量化遺傳部件、電路和代謝通量的實驗方法

遺傳部件庫：它們的創(chuàng)建、分析和本體表示

蛋白質(zhì)工程，包括計算設(shè)計

代謝工程和細胞制造，包括生物質(zhì)轉(zhuǎn)化

天然產(chǎn)物獲取、工程和生產(chǎn)

細胞編程的創(chuàng)造性和創(chuàng)新性應(yīng)用

醫(yī)療應(yīng)用、組織工程和治療細胞的編程

最小細胞設(shè)計和構(gòu)建

基因組學(xué)和基因組替換策略

病毒工程

合成生物學(xué)的自動化和機器人組裝平臺

DNA合成方法

宏基因組學(xué)和合成宏基因組學(xué)分析

生物信息學(xué)應(yīng)用于基因發(fā)現(xiàn)、化學(xué)信息學(xué)和通路構(gòu)建

基因優(yōu)化

轉(zhuǎn)錄和代謝組學(xué)的基因組規(guī)模測量方法

系統(tǒng)生物學(xué)和整合多種數(shù)據(jù)源的方法

體外和無細胞合成生物學(xué)和分子編程

核酸工程。

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