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Advances in drug development technologies are yielding innovative new therapies, from potentially lifesaving medicines to lifestyle products. In recent years, however, the cost of developing new drugs has soared, and concerns over drug resistance and pharmacoeconomics have come to the fore. Adverse reactions experienced at the clinical trial level serve as a constant reminder of the importance of rigorous safety and toxicity testing. Furthermore the advent of pharmacogenomics and ‘individualized’ approaches to therapy will demand a fresh approach to drug evaluation and healthcare delivery.

Clinical Pharmacology provides an essential role in integrating the expertise of all of the specialists and players who are active in meeting such challenges in modern biomedical practice.

藥物開發(fā)技術(shù)的進步正在催生創(chuàng)新的新療法，從可能挽救生命的藥物到生活方式產(chǎn)品。然而，近年來，開發(fā)新藥的成本飆升，對耐藥性和藥物經(jīng)濟學(xué)的擔(dān)憂也日益凸顯。臨床試驗階段的不良反應(yīng)不斷提醒人們嚴格的安全性和毒性測試的重要性。此外，藥物基因組學(xué)和“個性化”治療方法的出現(xiàn)將要求一種新的藥物評估和醫(yī)療保健方法。

臨床藥理學(xué)在整合所有積極應(yīng)對現(xiàn)代生物醫(yī)學(xué)實踐中此類挑戰(zhàn)的專家和參與者的專業(yè)知識方面發(fā)揮著重要作用。

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